Overview
This tests measures the by-products of microbial metabolism, and is particularly useful in detecting the presence of pathogenic microbial overgrowth. As a stand-alone test, the Organix Dysbiosis test is a great follow-up option to the Organix Comprehensive test, allowing the clinician to assess microbial overgrowth and guide and monitor targeted therapy in patients.
The urine contains unique products of microbial metabolism, which are used to measure small bowel yeast and bacterial overgrowth. With the exception of hippurate, the compounds measured in the Organix Dysbiosis test, such as D-arabinitol, are not normally produced by human cells. Unfriendly intestinal microorganisms, however, can manufacture them in relatively high quantities. These compounds are absorbed into the blood from the intestines and eventually appear in a urine organic acid test.
The LC/MS-MS test method - which is also used to screen newborns for metabolic disorders - requires very little sample preparation and processing. This technology provides more stability, accuracy, and sensitivity in measuring organic acids at low levels for optimum test results.
Only a single urine collection is required, which is easy for patients, leading to increased patient compliance.