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The Female/Male Saliva Profile III is a steroid hormone test to measure hormone levels and detect potential deficiencies.

Steroid hormones in the bloodstream are mostly (95-99%) bound to carrier proteins (hormone-binding globulins, albumin), and in this form they are unavailable to target tissues. Only the unbound fraction freely diffuses into tissues, including the salivary gland. Hormone levels in saliva therefore represent the quantity of the hormone that is currently available to target tissues and actively exerting specific effects on the body. Because of this, salivary hormone levels often relate to specific symptoms of hormone excesses or deficiencies. Research has demonstrated clear correlations between salivary hormone levels and reported symptoms. The rationale for and clinical utility of saliva testing is well documented. Hormones tested include: Estrogen (estradiol), Progesterone, DHEA and Testosterone, as well as diurnal (24 hour) Cortisol levels.