This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.
Elispot looks at the T cell response and IGG/IGM looks at B cells/Antibodies.
Some people don't produce antibodies and have a more active T cell response.
In an ideal world to assess an infection, a practitioner should look at both sides of the immune system response, in other words, Eli-spot for the T cells/cellular response and IGG/IGM for humoral/B cell/antibody response.
To check for recent antibodies (IGM) or past exposure antibodies (IGG) please run this test, but for the best overview of the immune system, combine it with the relevant Elispot test.
The Lyme/Borrelia IgG and IgM EIA test is designed to detect spirochetes called Borrelia burgdorferi, which can trigger Lyme disease when transmitted to the human body by a tick bite. Often there are no complications with the infection and it can be eliminated or controlled by a strong immune defense mechanism. If the immune defense is not strong enough, the infection can cause chronic symptoms (e.g. in the joints).
It is also possible that a tick bite transmits other pathogens along with Borrelia burgdorferi (e.g. Rickettsia, Babesia and Ehrlichia). The most important pathogens of Lyme Borreliosis are Borrelia burgdorferi, Borrelia garinii and Borrelia afzelii, which are closely related to the Syphilis pathogen Treponema pallidum.
Indication:
- to diagnose chronic Lyme disease
- to diagnose acute Lyme disease
- to determine the duration of therapy
- to monitor treatment results after a Lyme therapy