Borrelia DNA-PCR

Overview

The Borrelia DNA-PCR test uses polymerase chain reaction technology to detect genetic material from Borrelia species in a blood sample. PCR directly identifies Borrelia DNA rather than measuring antibody responses, offering a different perspective from serological testing.

This test may be clinically useful when symptoms or exposure history raise questions about Borrelia presence and antibody-based tests do not provide sufficient clarity. PCR detection can add context in early stages of illness or in situations where antibody responses are delayed, absent or difficult to interpret.

Practitioners typically interpret results alongside symptom history, timing of exposure, previous laboratory findings and consideration of other tick-borne organisms. Reviewing these factors together supports informed discussions with clients about investigation pathways and clinical context.