Functional Tests

H. Pylori (stand alone)

Overview

Methodology

Quantitative Polymerase Chain Reaction (qPCR), a molecular DNA laboratory technique, to identify H. Pylori in the sample.

Analytes:

  • H. pylori
    • Virulence Factor, babA
    • Virulence Factor, cabA
    • Virulence Factor, cabPAI
    • Virulence Factor, dupA
    • Virulence Factor, iceA
    • Virulence Factor, opiA
  • Antibiotic Resistance Genes, phenotypes
    • Clarithromycin
    • Fluoroquinolones
    • Tetracycline
    • Amoxicillin

Indications

H. Pylori (stand alone)

Recent studies have shown that nearly 50% of the world's population may harbor H. pylori. And, although many carriers are asymptomatic, H. pylori is known to have a causative role in ulcers, chronic gastritis, and stomach cancer.

Additionally, in early phases of colonization, individuals may experience hypochlorhydria followed by a change to hyper aciduria. Over time, additional H. pylori strains may colonize, including those with Virulence Factors and increased disease potential.

This test is also good to use as a follow-up to a GI-MAP test after H. pylori treatment, to monitor successful therapy.

 

Practical

Specimen

Stool sample 

Container

  • 1x orange-capped stool vial

Patient preparation

  • Please refrain from taking aspirin for two days prior to collecting your sample.
  • Never discontinue prescription medication without first consulting your physician.


Note: This test can be ordered as a stand-alone. H. pylori and virulence factors are included in the GI-MAP and GI-MAP plus Zonulin tests.

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Research