Functional Tests

LCMS saliva steroid panel 23

Overview

The LCMS saliva steroid panel measures multiple steroid hormones and related analytes in saliva using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Analytes include oestrogens, progesterone-related compounds, androgens, adrenal steroids, melatonin and selected synthetic or pharmaceutical compounds, providing a detailed salivary hormone profile.

This test may be clinically useful when symptoms suggest complex hormone pattern changes involving adrenal, sex or neuroactive steroids. Measuring multiple hormones simultaneously allows practitioners to observe relative levels and relationships across hormone groups rather than viewing markers in isolation.

Practitioners typically interpret results alongside clinical history, symptom presentation, menstrual or life stage context, medication or supplement use and other relevant laboratory data. This integrated approach supports informed discussions with clients about hormone-related patterns and further assessment considerations.

Indications


  • Hormone-related symptoms: changes linked to sex hormone balance.
  • Stress-related symptoms: altered stress resilience or pressure tolerance.
  • Menstrual cycle concerns: irregular cycles or cycle-related symptoms.
  • Androgen-related symptoms: changes in hair growth, skin or libido.
  • Fatigue patterns: low energy or altered daily stamina.
  • Sleep disturbances: difficulties with sleep quality or timing.
  • Metabolic concerns: weight changes or metabolic imbalance.
  • Mood changes: irritability, low mood or emotional variability.
  • Reproductive health concerns: fertility-related symptoms or hormonal transitions.

Practical

Downloads

Research


•"A Pilot Study Evaluating the Effectiveness of a Mindfulness-Based Intervention on Cortisol Awakening Response and Health Outcomes Among Law Enforcement Officers." Christopher MS, Goerling RJ, Rogers BS, Hunsinger M, Baron G, Bergman AL, Zava DT. J Police Criminal Psych 2015;31:15-28.

•"Female social and sexual interest across the menstrual cycle: the roles of pain, sleep and hormones.” Guillermo CJ, Manlove HA, Gray PB, Zava DT, Marrs CR. BMC-Womens Health 2010; 10(19):1-10.

• “Physical Competition Increases Dehydroepiandrosterone (DHEA) and Androstenedione rather than Testosterone among Juvenile Boy Soccer Players.” McHale TS, Zava DT, Hales D, Gray PB. Adaptive Human Behavior & Physiology, 2016;2:44-56.

• “Pilot study: absorption and efficacy of multiple hormones delivered in a single cream applied to the mucous membranes of the labia and vagina.” Glaser RL, Zava DT, Wurtzbacher D. Gynecologic and Obstetric Investigation 2008; 66(2):111-8.