Functional Tests

Male Blood Profile I (E2, E1, E3, Pg T, DS, C, SHBG, & PSA)

Overview

The Male Blood Profile I measures a panel of hormones and related markers using a bloodspot sample, including testosterone, estradiol, dehydroepiandrosterone sulfate, cortisol, sex hormone binding globulin and prostate specific antigen. Together, these markers provide insight into androgen status, adrenal activity and prostate-related physiology.

Clinically, this profile may be useful when men present with symptoms suggestive of altered hormone balance, such as reduced libido, changes in mood, energy or body composition. The inclusion of oestradiol and SHBG allows assessment of hormone balance and bioavailability, while cortisol adds context related to stress and adrenal function.

Practitioners typically interpret results alongside clinical history, age, lifestyle factors, body composition, medications and other laboratory findings. When reviewed in context, the profile can support informed discussions with clients about male hormone patterns and endocrine balance.

Indications


  • Androgen deficiency symptoms: low libido, erectile dysfunction or reduced sexual interest.
  • Mood symptoms: irritability, low mood or depressive symptoms.
  • Body composition changes: loss of muscle mass, increased fat mass or weight gain.
  • Energy symptoms: persistent fatigue or reduced physical stamina.
  • Metabolic concerns: features of metabolic syndrome or adverse lipid changes.
  • Sleep disturbance: difficulty falling or staying asleep.
  • Bone health concerns: osteoporosis or reduced bone density risk.
  • Prostate monitoring: assessment alongside prostate-related symptoms or risk factors.
  • Stress-related symptoms: symptoms associated with altered cortisol production

Practical

Test type:

Hormonal: Adrenal function, male hormones, stress hormones, thyroid hormones, prostate specific antigen (PSA)

Sample required:

Bloodspot

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Research