Functional Tests

OMX - Urine

Overview

The OMX™ Organic Metabolomics Test provides a comprehensive analysis of urine metabolites including organic acids, amino acids and other biochemical markers. The panel is designed to reflect activity across major metabolic pathways such as mitochondrial energy production, amino acid turnover, nutrient utilisation, detoxification-related processes and microbial metabolism. Results are organised into pathway-based categories to offer a clear view of metabolic relationships and potential areas of imbalance.

The test may be clinically useful when exploring patterns related to fatigue, low mood, cognitive changes, physical discomfort or stress resilience. By assessing metabolites linked with mitochondrial output, neurotransmitter pathways, B-vitamin utilisation, oxidative stress and amino acid metabolism, the profile can help highlight areas where biochemical processes may be under increased demand. The pathway-grouped layout allows for interpretation of interconnected metabolic trends rather than isolated markers.

OMX™ provides a structured way to evaluate metabolic function and nutrient status, supporting clinical interpretation when assessing complex or multi-system presentations. The breadth of markers included offers a detailed overview of metabolic signatures that may relate to energy production, mood, physical comfort or overall biochemical balance.

Indications


  • Fatigue or low energy: Persistent tiredness, reduced stamina or feeling easily depleted.
  • Mood changes: Low mood, irritability or emotional fluctuation.
  • Cognitive difficulties: Poor focus, forgetfulness or reduced mental clarity.
  • Stress-related symptoms: Feeling overwhelmed, tense or struggling with resilience.
  • Inflammation-type discomfort: Ongoing aches, stiffness or general physical sensitivity.
  • Blood sugar fluctuations: Variable energy after meals, cravings or changes in appetite.
  • Cardiovascular-related symptoms: Occasional palpitations, reduced endurance or sensations of sluggish circulation.
  • Digestive discomfort: Bloating, irregular bowel habits or unsettled digestion.
  • Skin symptoms: Irritation, breakouts or sensitivity.
  • Sleep disturbances: Difficulty falling asleep, disrupted sleep or waking unrefreshed.
  • Weight changes: Gradual or unexplained changes in weight or appetite.

Practical

Specimen

Urine

Please be aware that urine sampling is representative of recent dietary intake and metabolism of amino acids, it is more variable than in plasma. It is useful for controlled diets or to assess for efficacy of recent dietary changes (typically last 24/48 hours). Amino acid levels in urine can be influenced by abnormal kidney function and is ideal for children and adults as it is conveniently collected at home.

Container

Yellow capped Cup

Patient preparation

  • Avoid consuming fruits, jams, and jellies for 48 hours prior to collection


Downloads

Research

  1.  U.S. Department of Health and Human Services. (2016, March 9). Metabolomics Overview. National Institutes of Health. Retrieved November 23, 2021
  2. Hood, L. as cited in Miller, I.J., Peters, S.R., Overmyer, K.A. et al. Real-time health monitoring through urine metabolomics. npj Digit. Med. 2, 109 (2019). 
  3. Beger RD, Dunn W, Schmidt MA, et al. Metabolomics enables precision medicine: "A White Paper, Community Perspective". Metabolomics. 2016;12(10):149.