Functional Tests

OMX - Urine+Plasma

Overview

Overview

Understanding an individual's metabolome, combined with their medical history and lifestyle, allows clinicians to establish a larger picture and provide support from the bottom up. Ideally, practitioners will use OMX to establish a baseline metabolic signature for healthy patients. The baseline could be used for future comparison if symptoms, disease, or illness occurs.

Analytes


Metabolic processing
  • Glucose
  • Pyruvic Acid
  • Lactic Acid
  • Alanine
  • Citric Acid
  • cis-Aconitic Acid
  • Isocitric Acid
  • alpha-Ketoglutaric acid
  • Succinic acid
  • Fumaric Acid
  • Malic Acid
  • Adipic Acid
  • Suberic Acid
  • Pimelic Acid
  • Hxanoylglycine
  • Suberylglycline
  • 3-Phenylpropionylglycine
  • Thylmalonic acid
  • 2-Methylsuccinic Acid
  • Beta-Hydroxybutyric Acid









Nutrition

  • Branched chain Alpha-Keto organic Acids
  • Aplha- Ketoglutaric Acid
  • Pyruvic Acid
  • Methylmalonic Acid
  • Formiminoglutamic Acid
  • Pyridoxic Acid
  • Xanthurenic Acid
  • Beta-Hydroxyisovaleric Acid
  • Quercetin
  • Tartaric Acid
  • 1-Methylhistidine
  • Carnosine
  • Anserine
  • Fructose













Amino acid and Protein Metabolism

  • Phenylalanine
  • Phenylacetic Acid
  • Tyrosine
  • Homovanillic Acid
  • Vannilylmandelic Acid
  • 4-Hydroxyphenylpyruvic Acid
  • Homogentisic Acid
  • Total branched chain amino acids
  • Valine
  • alpha-Ketoisovaleric acid
  • Isoleucine/Allo-Isoleucine
  • alphat-keto-beta-methyivaleric Acid
  • Leucine
  • alpha-Ketoisocaproic Acid
  • Tryptophan
  • 5-Hydroxyindoleacetic Acid
  • Kynurenine
  • KT Radio
  • Hydroxykynurenine
  • Xanthurenic Acid
  • Anthranilic Acid
  • Picolinic Acid
  • Kynurenic Acid
  • Quinolinic Acid
  • Methionine
  • Homocystine
  • Cystathionine
  • Sulfocysteine
  • Taurine
  • Cystine
  • alpha-Hydroxybutyric Acid
  • Pyroglutamic Acid
  • Histidine
  • 3-Methylhistidine
  • Beta-Alanine
  • Threonine
  • Glycine
  • Serine
  • Sarcosine
  • Ethanolamine
  • Phosphoethanolamine
  • Lysine
  • alpha-Aminoadipic Acid
  • Glutaric Acid
  • Glutamine
  • Glutamic Acid
  • Glutamine/Gluramate Ratio
  • Asparagine
  • Aspartic Acid
  • Proline
  • Hydroxyproline
  • Glycylproline
Toxic Impacts


8-Hydroxy-2'-deoxyguanosine
2-Methylhippuric Acid
Mandelic Acid
Benzoylform
Glucaric Acid
Arginine
Citrulline
Ornithine
Homocitrulline
Arginosuccinic Acid
Orotic Acid
Microalbumin
Phospate
Creatinine
Oxalic Acid

Stress and Mood


Amino butiric Acid
Homovanillic Acid
Vannylmandelic Acid
5-Hydroxyindolacetic Acid
Cortisol

Microbial Metabolites

4-Hydroxyphenylacetic Acid
Indolacetic Acid
3,4 Dihydrocinnamic Acid
3,5-Dihydroxybenzoic Acid
4-Hydroxybenzoic Acid
Benzoic Acid
Hippuric Acid
Equol
Arabinitol



Methodology

LC-MS/MS

Indications

This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.

The OMX?™ Organic Metabolomics test evaluates urine and plasma metabolites—including organic acids, amino acids, and other key compounds—to assist practitioners in unraveling their patient’s metabolic pathways, revealing their unique Metabolic Signature 

OMX™ metabolomic testing goes beyond traditional organic acid testing. OMX characterizes metabolic phenotypes by presenting analytes in pathway categories to more easily identify metabolomic deviations that can underlie—and even precede—disease

Indications

  • Mood Disorders 
  • Mitochondrial Dysfunction 
  • Fatigue 
  • Chronic Stress 
  • Inflammation Depression
  • Cardiovascular disease
  • Neurocognitive decline 
  • Diabetes

Please note that this test has a serum sample and requires a full blood draw

Practical

Specimen

Urine and plasma

Please be aware that plasma amino acids, if fasting sampling, can be indicative of the amino acid pool (steady state) and are not influenced by short term intake or dietary fluctuations. This is useful for cases of mood disorders or erratic diets. Compared to urine samples, they convey a slightly better look at amino acid requirements and they are not influenced by kidney function.

Container

1x Yellow capped Cup

1x Transfer vial

Patient preparation

  • Phlebotomy service required.
  • Avoid consuming fruits, jams, and jellies for 48 hours prior to collection
  • Patient must have fasted for the past eight (8) hours.

Research